Crane Health Technology Research Federation is the supposed antagonist corporation of the Emotion Spectrum series along with Tog Enterprises. So far, little is known about them other than they are practically merged with Tog Enterprises, with Crane being more of a publisher and Tog Enterprises being more of a developer. (It is actually later figured out that although they are partially allies, they actually manufacture and publish different products.) Greyed Out explores the Crane Health Technology Research Federation, while Gustav's side of that story in the third ES game will explore Tog Enterprises.

Their base of operations consists of two similar facilities, A and B. These are known as Crane Federation Facilities and are Preco's base of operation.

Community content is available under CC-BY-SA unless otherwise noted.